Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 9/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214410 | 1.00 | SRD5A1 (0.54) | SRD5A1SRD5A2ARALDH1A1 | |
| SCHEMBL5214401 | 1.00 | SRD5A1 (0.54) | SRD5A1SRD5A2ARALDH1A1 | |
| SCHEMBL5214113 | 0.91 | SRD5A1 (0.53) | SRD5A1SRD5A2AR | |
| SCHEMBL5214106 | 0.91 | SRD5A1 (0.53) | SRD5A1SRD5A2AR | |
| SCHEMBL5211218 | 0.90 | SRD5A1 (0.53) | SRD5A1SRD5A2AR | |
| SCHEMBL5211228 | 0.90 | SRD5A1 (0.53) | SRD5A1SRD5A2AR | |
| SCHEMBL5214264 | 0.89 | SRD5A1 (0.54) | SRD5A1SRD5A2AR | |
| SCHEMBL5214262 | 0.89 | SRD5A1 (0.54) | SRD5A1SRD5A2AR | |
| SCHEMBL5213927 | 0.89 | SRD5A2 (0.59) | SRD5A1SRD5A2AR | |
| SCHEMBL5213919 | 0.89 | SRD5A2 (0.59) | SRD5A1SRD5A2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645974-B2 | Administering an androstamide compound; osteoporosis, anticancer agents, glandular disorders | MERCK & CO., INC. | 2003-11-11 | — | — | US | claimed |
| US-20030065004-A1 | Androgen receptor modulators and methods for use thereof | MERCK SHARP & DOHME CORP. | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065004-A1 | Androgen receptor modulators and methods for use thereof | AR, FSHR, SHBG | SRD5A1 58/4885SRD5A2 80/4885AR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.