SCHEMBL7080412

SCHEMBL7080412

C=C(C)C(=O)OCCCCCCCCCCCCCCCCCC.C=C(C=CC(=O)O)C(=O)OC1CC2CCC1(C)C2(C)C.C=CC(=O)OCCCCCCCCCCCCCCCCCC.C=CC(=O)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
HTT P42858 3/20 0.45
MAPT P10636 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
KDM4E B2RXH2 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
PLA2G1B P04054 1/20 0.43
MAPK1 P28482 1/20 0.43
RAD52 P43351 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
TSHR P16473 3/20 0.40
HCAR2 Q8TDS4 2/20 0.39
CYP2C19 P33261 1/20 0.38
EPHX2 P34913 1/20 0.36
ELANE P08246 2/20 0.35
CYP19A1 P11511 2/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083081 1.00 LMNA (0.45) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL7083311 1.00 LMNA (0.45) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL28319877 0.90 LMNA (0.50) LMNAHTTMAPTNPSR1KDM4E
Methacrylic Acid SCHEMBL7080056 0.89 LMNA (0.49) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL7958498 0.88 LMNA (0.46) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL23855038 0.88 LMNA (0.52) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL8777327 0.88 LMNA (0.52) LMNAHTTMAPTNPSR1KDM4E
Methacrylic Acid SCHEMBL8777382 0.87 LMNA (0.50) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL35201 0.86 HTT (0.40) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL7974759 0.86 LMNA (0.48) LMNAHTTMAPTNPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811042-B1 PRESSURE-SENSITIVE CRAYON ADHESIVE MINNESOTA MINING & MFG (US) 2003-07-09 EP claimed
US-5604268-A FRICTION ACTIVATED ACRYLATE ADHESIVE CONTAINING CRYSTALLINE MONOMER, WAXY, SOFT MONOMER, TACKIFYING MONOMER, ACID MONOMER, MACROMERIC UNIT, HIGHER ALKYL MONOMER, TACKIFIER ADDITIVE AND FILLER; STORAGE AND HANDLING STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-18 US claimed