SCHEMBL7080460

SCHEMBL7080460

C[Si](C)(C)CCOCOc1cc(COC2CN(OC(=O)O)CCC2c2ccc(OCCO)cc2)cc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7504338 0.91 REN (0.37) REN
SCHEMBL7079990 0.91 REN (0.38) REN
SCHEMBL6041389 0.91 REN (0.40) REN
SCHEMBL7079543 0.88 REN (0.39) REN
SCHEMBL6041608 0.86 REN (0.41) REN
SCHEMBL6043030 0.85 REN (0.40) REN
SCHEMBL7076694 0.85 REN (0.42) REN
SCHEMBL7081516 0.85 REN (0.49) REN
SCHEMBL7077071 0.84 REN (0.34) REN
SCHEMBL7503793 0.84 REN (0.36) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed