SCHEMBL708067

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL710789	0.90	PARP1 (0.43)	PARP1TNKSTNKS2TNK2TNK1
	SCHEMBL710412	0.87	PARP1 (0.62)	PARP1TNKSTNKS2TNK2TNK1
	SCHEMBL709133	0.87	PARP1 (0.61)	PARP1TNKSTNKS2TNK2TNK1
	SCHEMBL708319	0.86	PARP1 (0.56)	PARP1TNKSTNKS2TNK2TNK1
	SCHEMBL708538	0.80	DRD4 (0.44)	PARP1HTR7
	SCHEMBL709163	0.79	CYP2D6 (0.38)	PARP1TNKSTNKS2TNK2TNK1
	SCHEMBL710453	0.78	PARP1 (0.48)	PARP1TNKSTNKS2HTR7
	SCHEMBL709791	0.78	PARP1 (0.43)	PARP1TNKSPARP2
	SCHEMBL707779	0.78	PARP1 (0.43)	PARP1TNKSPARP2
	SCHEMBL708931	0.77	KDM4E (0.50)	PARP1TNKSTNKS2TNK2TNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.