SCHEMBL709791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707779	1.00	PARP1 (0.43)	PARP1HTR2AHTR2CHTR2BICAM1
	SCHEMBL707660	0.90	PARP1 (0.56)	PARP1PARP6PARP2PARP3
	SCHEMBL709162	0.89	PARP1 (0.57)	PARP1PARP6PARP2PARP3
	SCHEMBL6125339	0.89	PARP1 (0.43)	PARP1ALDH1A1MAPT
	SCHEMBL707773	0.89	PARP1 (0.55)	PARP1
	SCHEMBL708538	0.89	DRD4 (0.44)	PARP1HTR2AHTR2CKDM4EMEN1
	SCHEMBL709498	0.87	ALOX15 (0.50)	PARP1HTR2AHTR2CHTR2BKDM4E
	SCHEMBL709006	0.87	ALOX15 (0.50)	PARP1HTR2AHTR2CHTR2BKDM4E
	SCHEMBL710789	0.86	PARP1 (0.43)	PARP1KDM4EMEN1ALDH1A1MAPT
	SCHEMBL707519	0.86	PARP1 (0.49)	PARP1HTR2AHTR2CHTR2BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.