Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MTTP | P55157 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APOB | P04114 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795017 | 0.92 | TP53 (0.50) | TP53LMNAMAPTMTTPKDM4E | |
| SCHEMBL7135213 | 0.92 | GAA (0.48) | TP53LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL6789164 | 0.89 | TP53 (0.45) | TP53LMNAMAPTMTTPKDM4E | |
| SCHEMBL6795504 | 0.84 | MTTP (0.42) | TP53MAPTMTTPAPOB | |
| SCHEMBL6490959 | 0.80 | TP53 (0.43) | TP53LMNAMAPTMTTPAPOB | |
| SCHEMBL6789124 | 0.80 | TP53 (0.50) | TP53LMNAMAPTMTTPKDM4E | |
| SCHEMBL6800205 | 0.79 | TP53 (0.47) | TP53LMNAMAPTMTTPKDM4E | |
| SCHEMBL6787835 | 0.79 | MTTP (0.47) | TP53MAPTMTTPAPOB | |
| SCHEMBL6798726 | 0.78 | NPC1 (0.57) | TP53LMNAMAPTMTTPKDM4E | |
| SCHEMBL6787479 | 0.78 | AOC3 (0.52) | TP53LMNAMAPTMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |