Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.67 |
| ▸ | AR | P10275 | 6/20 | 0.65 |
| ▸ | PGR | P06401 | 5/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157184 | 1.00 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2SHBG | |
| SCHEMBL13216950 | 1.00 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2SHBG | |
| SCHEMBL29008753 | 1.00 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2SHBG | |
| SCHEMBL5017877 | 1.00 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2SHBG | |
| SCHEMBL14342104 | 1.00 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2SHBG | |
| SCHEMBL5974440 | 0.88 | CYP19A1 (0.51) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL7618203 | 0.88 | CYP19A1 (0.51) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL5973825 | 0.84 | CYP19A1 (0.62) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL1656778 | 0.84 | CYP19A1 (0.62) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL13809835 | 0.82 | CYP19A1 (0.60) | CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322660-A2 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | Schering AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002026759-A2 | 17α FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2002-04-04 | — | — | WO | disclosed |