Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.51 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974440 | 1.00 | CYP19A1 (0.51) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL7080880 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL13216950 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL14342104 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL5157184 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL29008753 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL5017877 | 0.88 | CYP19A1 (0.67) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL6386655 | 0.79 | AR (0.52) | CYP19A1AR | |
| SCHEMBL5974319 | 0.77 | AR (0.50) | ARPGRNR3C2 | |
| SCHEMBL6840796 | 0.77 | AR (0.50) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240179-A2 | 3-METHYLENE STEROID DERIVATIVES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Akzo Nobel N.V. (NL) | 2002-09-18 | — | — | EP | claimed |
| WO-2001040253-A2 | 3-METHYLENE STEROID DERIVATIVE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | AKZO NOBEL N.V. (NL) | 2001-06-07 | — | — | WO | claimed |
| EP-1240179-A2 | 3-METHYLENE STEROID DERIVATIVES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Akzo Nobel N.V. (NL) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001040253-A2 | 3-METHYLENE STEROID DERIVATIVE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | AKZO NOBEL N.V. (NL) | 2001-06-07 | — | — | WO | disclosed |