Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084770 | 0.90 | REN (0.35) | RENKLK7KDM2BTACR1 | |
| SCHEMBL7081010 | 0.89 | KDM2B (0.36) | RENKLK7KDM2BTACR1LRRK2 | |
| SCHEMBL7077071 | 0.88 | REN (0.34) | RENTACR1 | |
| SCHEMBL7074773 | 0.88 | REN (0.47) | REN | |
| SCHEMBL7076769 | 0.87 | REN (0.45) | REN | |
| SCHEMBL7083931 | 0.87 | KDM2B (0.36) | KLK7KDM2BTACR1LRRK2 | |
| SCHEMBL7079194 | 0.87 | KDM2B (0.37) | RENKLK7KDM2BTACR1LRRK2 | |
| SCHEMBL7076042 | 0.85 | REN (0.37) | RENKLK7KDM2BTACR1 | |
| SCHEMBL6043804 | 0.84 | REN (0.39) | RENKDM2BLRRK2 | |
| SCHEMBL7083194 | 0.83 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |