Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.42 |
| ▸ | FNTB | P49356 | 11/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979467 | 0.91 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6975064 | 0.90 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7088691 | 0.88 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087476 | 0.88 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087362 | 0.88 | FNTA (0.48) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982933 | 0.88 | FNTA (0.45) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6985593 | 0.86 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982183 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6974951 | 0.83 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6974275 | 0.82 | FNTA (0.43) | FNTAFNTBPGGT1BCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |