Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.48 |
| ▸ | FNTB | P49356 | 14/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974275 | 0.93 | FNTA (0.43) | FNTAFNTBPGGT1BCYP3A4MAPK1 | |
| SCHEMBL7088691 | 0.93 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6975064 | 0.93 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982933 | 0.92 | FNTA (0.45) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087340 | 0.92 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6985593 | 0.91 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087476 | 0.89 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982183 | 0.88 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7081046 | 0.88 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6974951 | 0.86 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| EP-1045846-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028315-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1999-06-10 | — | — | WO | disclosed |