Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL7088066 | 0.96 | HTR2A (0.33) | L3MBTL1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL7085988 | 0.82 | MEN1 (0.43) | L3MBTL1ALDH1A1LMNAMAPTPDPK1 | |
| SCHEMBL7082177 | 0.81 | PDPK1 (0.41) | ALDH1A1LMNAMAPTPDPK1HPGD | |
| SCHEMBL7086017 | 0.81 | POLB (0.33) | ALDH1A1LMNAMAPTTDP1PDPK1 | |
| Bromomethane SCHEMBL7081929 | 0.79 | KMT2A (0.44) | L3MBTL1ALDH1A1MAPTPDPK1HPGD | |
| SCHEMBL6554256 | 0.79 | ERCC5 (0.38) | ALDH1A1PDPK1NPC1RAB9ACHRM3 | |
| Bromomethane SCHEMBL7085436 | 0.78 | PDPK1 (0.32) | MAPTPDPK1CHRM3KMT2AMEN1 | |
| Bromomethane SCHEMBL7084864 | 0.78 | PDPK1 (0.39) | ALDH1A1LMNAMAPTPDPK1HPGD | |
| SCHEMBL7085713 | 0.78 | NPC1 (0.41) | ALDH1A1LMNAMAPTPDPK1HPGD | |
| SCHEMBL7086476 | 0.78 | PPARG (0.36) | ALDH1A1PDPK1NPC1RAB9ACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328524-B1 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-12-12 | — | — | EP | disclosed |
| EP-1328524-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032898-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |