Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL7087263 | 0.96 | SCN5A (0.37) | ERCC5FEN1KIF11SCN5ASCN9A | |
| SCHEMBL7085988 | 0.86 | MEN1 (0.43) | MAOBCHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL7082177 | 0.85 | PDPK1 (0.41) | KIF11CHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL3911903 | 0.85 | KCNN4 (0.41) | KCNK3CHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL14142417 | 0.85 | LMNA (0.45) | KCNK3MAOBCHRM3MEN1KMT2A | |
| SCHEMBL7085713 | 0.85 | NPC1 (0.41) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| Bromomethane SCHEMBL7081929 | 0.83 | KMT2A (0.44) | MAOBCHRM3CHRM2CHRM1MEN1 | |
| SCHEMBL543310 | 0.83 | KCNN4 (0.40) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| Bromomethane SCHEMBL7084864 | 0.82 | PDPK1 (0.39) | KIF11CHRM3CHRM2CHRM1MEN1 | |
| Bromomethane SCHEMBL120034 | 0.82 | KCNN4 (0.39) | KCNK3CHRM3CHRM2CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328524-B1 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-12-12 | — | — | EP | disclosed |
| EP-1325001-B1 | ANTICHOLINERGIC AGENTS THAT CAN BE USED AS MEDICAMENTS AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1382606-A2 | 8-azabicyclo[3.2.1]octane derivatives and their use as anticholinergics | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1328524-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1325001-A1 | ANTICHOLINERGIC AGENTS THAT CAN BE USED AS MEDICAMENTS AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002032898-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032899-A1 | NOVEL ANTICHOLINERGIC AGENTS THAT CAN BE USED AS MEDICAMENTS AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |