Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081178 | 1.00 | GCGR (0.34) | GCGRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8060059 | 0.92 | KDM4E (0.33) | GCGRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8060057 | 0.92 | KDM4E (0.33) | GCGRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8065574 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8063628 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8065570 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8063626 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8336346 | 0.90 | L3MBTL1 (0.32) | L3MBTL1HTT | |
| SCHEMBL8336348 | 0.90 | L3MBTL1 (0.32) | L3MBTL1HTT | |
| SCHEMBL8060031 | 0.89 | KDM4E (0.32) | KDM4EALDH1A1GAAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140362-A | INHIBITING MAMMALIAN CELL GROWTH IN BENIGN OR MALIGNANT TUMORS COMPRISING TREATING SAID CELLS WITH AN EFFECTIVE AMOUNT OF A N-ACETONYLARYLAMIDES COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-10-31 | — | — | US | claimed |
| EP-0815727-B1 | Use of N-acetonylbenzamides for controlling resistant fungi | ROHM & HAAS (US) | 2000-08-16 | — | — | EP | claimed |
| EP-0815727-A1 | Method for controlling resistant fungi | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0878192-B1 | Treating protozoal infections | ALLEGHENY UNIVERSITY OF THE HE (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6500405-B1 | EVALUATING THE SENSITIVITY OF A TEST CELL POPULATION TO AN ANTITUBULIN COMPOUND COMPRISING INCUBATING CELLS OR CELL EXTRACTS WITH AN AMIDE PROBE IN THE PRESENCE AND ABSENCE OF AN ANTITUBULIN TEST COMPOUND | DOW AGROSCIENCES LLC | 2002-12-31 | — | — | US | disclosed |
| EP-0816328-B1 | Process for the manufacture of acetonylbenzamides | DOW AGROSCIENCES LLC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6140362-A | INHIBITING MAMMALIAN CELL GROWTH IN BENIGN OR MALIGNANT TUMORS COMPRISING TREATING SAID CELLS WITH AN EFFECTIVE AMOUNT OF A N-ACETONYLARYLAMIDES COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-6107316-A | USING AN HETEROCYCLIC AMIDE COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0815727-B1 | Use of N-acetonylbenzamides for controlling resistant fungi | ROHM & HAAS (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-0843018-B1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5891918-A | Method for controlling resistant fungi | ROHM AND HAAS COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| US-5874466-A | REACTING AMINE AND ACYL CHLORIDE, HYDROGENOLYSIS | ROHM AND HAAS COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0880893-A1 | Method for controlling algae | ROHM AND HAAS COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0878192-A2 | Method for treating protozoal infections | Allegheny University of The Health Sciences (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0843018-A1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM AND HAAS COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0834311-A1 | Method for inhibiting the growth of mammalian cells | ROHM AND HAAS COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0815727-A1 | Method for controlling resistant fungi | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0816328-A2 | Process for the manufacture of acetonylbenzamides | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |