Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946383 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1HRH3MEN1 | |
| SCHEMBL1454080 | 0.77 | MAPT (0.56) | ALDH1A1MAPTL3MBTL1HRH3MEN1 | |
| SCHEMBL7098162 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1HRH3MEN1 | |
| SCHEMBL232188 | 0.77 | MAPT (0.78) | ALDH1A1MAPTL3MBTL1HRH3CYP1A2 | |
| SCHEMBL11868348 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1MEN1CYP1A2 | |
| SCHEMBL6416019 | 0.75 | MAPT (0.74) | ALDH1A1MAPTL3MBTL1HRH3CYP1A2 | |
| SCHEMBL1562142 | 0.75 | MAPT (0.74) | ALDH1A1MAPTL3MBTL1HRH3CYP1A2 | |
| SCHEMBL9572882 | 0.74 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1HRH3MEN1 | |
| SCHEMBL1203153 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1HRH3CYP1A2 | |
| SCHEMBL23450556 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079829-B1 | USE OF BENZOFUROXAN DERIVATIVES IN TREATING ANGINA PECTORIS | TORRENT PHARMACEUTICALS LTD (IN) | 2003-07-23 | — | — | EP | disclosed |