SCHEMBL7081735

SCHEMBL7081735

COc1ccccc1COCCCOc1ccc(C2CCN(OC(=O)OC(C)(C)C)CC2OCc2cc(OC)c3ccccc3c2OC)cc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7084760 0.94 REN (0.54) REN
SCHEMBL7076766 0.94 REN (0.54) REN
SCHEMBL7079511 0.93 REN (0.54) REN
SCHEMBL7079908 0.92 REN (0.52) REN
SCHEMBL7078187 0.91 REN (0.52) REN
SCHEMBL7078446 0.91 REN (0.51) REN
SCHEMBL7078005 0.91 REN (0.60) REN
SCHEMBL7080796 0.90 REN (0.51) REN
SCHEMBL7083159 0.90 REN (0.51) REN
SCHEMBL7084145 0.89 REN (0.49) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed