Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682404 | 0.81 | HSD11B1 (0.50) | HSD11B1MAOBMAOACYP2A6MEN1 | |
| SCHEMBL13216074 | 0.78 | HSD11B1 (0.54) | HSD11B1MEN1KMT2A | |
| SCHEMBL8766773 | 0.78 | HSD11B1 (0.56) | HSD11B1MAOBMAOACNR2BACE1 | |
| SCHEMBL6901742 | 0.75 | HSD11B1 (0.57) | HSD11B1MAOBMAOACNR2EPHX2 | |
| SCHEMBL25611079 | 0.72 | HSD11B1 (0.51) | HSD11B1MAOBMAOACNR2BACE1 | |
| SCHEMBL6895204 | 0.71 | HSD11B1 (0.50) | HSD11B1MAOBMAOACNR2ALDH1A1 | |
| SCHEMBL14175565 | 0.71 | HSD11B1 (0.57) | HSD11B1CNR2ALDH1A1BACE1CTSD | |
| Hydrochloric Acid SCHEMBL6898935 | 0.70 | HSD11B1 (0.63) | HSD11B1MAOBMAOAALDH1A1BACE1 | |
| SCHEMBL13216336 | 0.70 | HSD11B1 (1.00) | HSD11B1MEN1KMT2A | |
| SCHEMBL6934361 | 0.69 | HSD11B1 (0.51) | HSD11B1MAOBMAOACNR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |