Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771037 | 0.90 | ALDH1A1 (0.62) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPK1 | |
| SCHEMBL11728744 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPK1 | |
| SCHEMBL7082056 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPT | |
| SCHEMBL6324751 | 0.77 | SRD5A2 (0.51) | ALDH1A1MAPK1GAAMAPTPOLB | |
| SCHEMBL7079376 | 0.77 | MAPK13 (0.67) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPK1 | |
| SCHEMBL7080468 | 0.77 | KMT2A (0.51) | SMN1; SMN2KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL7466939 | 0.77 | ALDH1A1 (0.56) | KMT2AALDH1A1HTTMAPTMEN1 | |
| SCHEMBL6951515 | 0.75 | SMN1; SMN2 (0.69) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPT | |
| SCHEMBL6314599 | 0.75 | MAPK1 (0.68) | SMN1; SMN2HSD17B10KMT2AALDH1A1MAPK1 | |
| SCHEMBL5173228 | 0.74 | MAPK13 (0.61) | SMN1; SMN2KMT2AALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | disclosed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | MAPKAPK2, MAP3K2, MAP3K1 | SMN1; SMN2 4425/4885HSD17B10 648/4885KMT2A 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.