Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082135 | 1.00 | HSD17B10 (0.46) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL7082138 | 0.82 | HSD17B10 (0.47) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL8808758 | 0.75 | HSD17B10 (0.62) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL17988351 | 0.75 | HSD17B10 (0.62) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL12151239 | 0.70 | — | — | |
| SCHEMBL10675360 | 0.69 | — | — | |
| SCHEMBL9655392 | 0.67 | LMNA (0.66) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL9655389 | 0.67 | LMNA (0.66) | HSD17B10GAALMNAALDH1A1GFER | |
| SCHEMBL183532 | 0.66 | — | — | |
| SCHEMBL13134021 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |