Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162521 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8164966 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8157470 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8164009 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8148979 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8162827 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8158463 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8149988 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8162369 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 | |
| SCHEMBL8161707 | 0.82 | LMNA (0.61) | LMNATSHRFFAR4PPARAFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |