Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 18/20 | 0.66 |
| ▸ | F10 | P00742 | 18/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.66 |
| ▸ | F2 | P00734 | 16/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7078079 | 0.99 | PRSS1 (0.65) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL7081931 | 0.94 | F10 (0.62) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7084789 | 0.94 | PRSS1 (0.64) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7078179 | 0.94 | PRSS1 (0.64) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL7084065 | 0.93 | F10 (0.61) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7077225 | 0.93 | PRSS1 (0.63) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7080750 | 0.93 | PRSS1 (0.60) | PRSS1F10PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7081948 | 0.93 | F10 (0.59) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7082068 | 0.92 | PRSS1 (0.59) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7077218 | 0.92 | PRSS1 (0.55) | PRSS1F10PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | PRSS1 398/4885F10 5/4885PRSS2 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.