Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081931 | 0.99 | F10 (0.62) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7081014 | 0.97 | F10 (0.59) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7081948 | 0.96 | F10 (0.59) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7078079 | 0.94 | PRSS1 (0.65) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7082503 | 0.93 | PRSS1 (0.66) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7080818 | 0.91 | F10 (0.50) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7078126 | 0.90 | F10 (0.51) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7081211 | 0.90 | F10 (0.57) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7083933 | 0.89 | F10 (0.58) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7084324 | 0.89 | F10 (0.58) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | F10 5/4885PRSS1 398/4885PRSS2 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.