Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043272 | 0.90 | REN (0.51) | RENMEN1KMT2A | |
| SCHEMBL6043267 | 0.90 | REN (0.51) | RENMEN1KMT2A | |
| SCHEMBL7080933 | 0.86 | REN (0.55) | RENMEN1KMT2A | |
| SCHEMBL7076614 | 0.86 | REN (0.55) | RENMEN1KMT2A | |
| SCHEMBL7079425 | 0.85 | REN (0.54) | REN | |
| SCHEMBL7137310 | 0.85 | REN (0.48) | REN | |
| SCHEMBL7078964 | 0.84 | REN (0.55) | RENMEN1KMT2A | |
| SCHEMBL7075270 | 0.84 | MEN1 (0.42) | RENMEN1KMT2A | |
| SCHEMBL7540005 | 0.84 | MEN1 (0.43) | RENMEN1KMT2A | |
| SCHEMBL7075237 | 0.83 | REN (0.56) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |