Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 3/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.56 |
| ▸ | PPARD | Q03181 | 6/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28267991 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28861099 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28268119 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28266436 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Tetradecanamide SCHEMBL28868494 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL29103349 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28266428 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28266435 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28266429 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 | |
| Alcohol SCHEMBL28267994 | 1.00 | SOAT1 (0.68) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973529-A1 | DISINTEGRATING LOADABLE TABLETS | LifeCycle Pharma A/S (DK) | 2008-10-01 | — | — | EP | claimed |
| EP-1511798-B1 | METHOD FOR MAKING POLYOLEFIN NANOCOMPOSITES | BASELL POLIOLEFINE SRL (IT) | 2008-07-30 | — | — | EP | claimed |
| WO-2007076874-A1 | DISINTEGRATING LOADABLE TABLETS | LIFECYCLE PHARMA A/S (DK) | 2007-07-12 | — | — | WO | claimed |
| EP-1765297-A2 | POROUS TABLETS AS CARRIERS FOR LIQUID FORMULATIONS | LifeCycle Pharma A/S (DK) | 2007-03-28 | — | — | EP | claimed |
| WO-2006000229-A2 | POROUS TABLETS AS CARRIERS FOR LIQUID FORMULATIONS | LIFECYCLE PHARMA A/S (DK) | 2006-01-05 | — | — | WO | claimed |
| EP-1511798-A2 | METHOD FOR MAKING POLYOLEFIN NANOCOMPOSITES | Basell Poliolefine Italia S.p.A. (IT) | 2005-03-09 | — | — | EP | claimed |
| US-6864308-B2 | Method for making polyolefin nanocomposites | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-03-08 | — | — | US | claimed |
| WO-2003106549-A2 | METHOD FOR MAKING POLYOLEFIN NANOCOMPOSITES | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-12-24 | — | — | WO | claimed |
| US-20030232912-A1 | Method for making polyolefin nanocomposites | BASELL POLIOLEFINE ITALIA S.P.A (IT) | 2003-12-18 | — | — | US | claimed |
| CN-118235092-A | Polycyclic aromatic hydrocarbon-based photocurable resin composition | 日产化学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023085414-A1 | POLYCYCLIC AROMATIC HYDROCARBON-BASED PHOTO-CURABLE RESIN COMPOSITION | 日産化学株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-115135637-A | Polyurethane compounds | 大金工业株式会社 | 2022-09-30 | — | — | CN | disclosed |
| CN-113527612-A | Polyurethane compounds | 大金工业株式会社 | 2021-10-22 | — | — | CN | disclosed |
| US-11129815-B2 | Solid dispersions comprising tacrolimus | VELOXIS PHARMACEUTICALS INC. (US) | 2021-09-28 | — | — | US | disclosed |
| WO-2002085360-A1 | OPTIMIZED PROCEDURES FOR THE MANUFACTURE OF PAROXETINE SALTS | PENTECH PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-20020032220-A1 | Formulations comprising dissolved paroxetine | SMITHKLINE BEECHAM PLC | 2002-03-14 | — | — | US | disclosed |
| EP-1077685-A2 | NOVEL FORMULATION CONTAINING PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-02-28 | — | — | EP | disclosed |
| EP-1033986-A1 | FORMULATIONS COMPRISING DISSOLVED PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999058116-A2 | NOVEL FORMULATION CONTAINING PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999026625-A1 | FORMULATIONS COMPRISING DISSOLVED PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129815-B2 | Solid dispersions comprising tacrolimus | TSLP, CD69, CD40LG | SOAT1 2363/4885MEN1 2130/4885KMT2A 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.