Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076322 | 0.91 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7079506 | 0.90 | F10 (0.50) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7082839 | 0.85 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7135037 | 0.82 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7080631 | 0.80 | F10 (0.56) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7475336 | 0.80 | F10 (0.63) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7008413 | 0.79 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2073976 | 0.79 | F10 (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2070983 | 0.79 | F10 (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2070569 | 0.79 | F10 (0.45) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322618-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR X A? INHIBITORS 14) | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | claimed |
| WO-2002024654-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR XA INHIBITORS 14) | MERCK PATENT GMBH (DE) | 2002-03-28 | — | — | WO | claimed |
| EP-1322618-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR X A? INHIBITORS 14) | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024654-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR XA INHIBITORS 14) | MERCK PATENT GMBH (DE) | 2002-03-28 | — | — | WO | disclosed |