Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6778511 | 0.99 | OPRD1 (0.71) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL4681851 | 0.90 | OPRD1 (0.73) | OPRD1OPRM1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL6772092 | 0.90 | OPRD1 (0.72) | OPRD1OPRM1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL6768627 | 0.88 | OPRD1 (0.69) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL6769093 | 0.87 | OPRD1 (0.71) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL6773667 | 0.86 | OPRD1 (0.69) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL7086156 | 0.86 | OPRD1 (0.69) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL4680591 | 0.85 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL7083492 | 0.85 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL6773724 | 0.85 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242402-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | claimed |