Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083237 | 1.00 | ATM (0.70) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL27411593 | 0.93 | HCAR2 (0.64) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL21126695 | 0.88 | ATM (0.52) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL7083152 | 0.88 | HCAR2 (0.59) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL1171459 | 0.88 | HCAR2 (0.59) | ATMHCAR2HPGDTSHRMAPT | |
| Hydrochloric Acid SCHEMBL8108663 | 0.86 | HCAR2 (0.57) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL21126304 | 0.86 | ATM (0.46) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL28007434 | 0.85 | ATM (0.48) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL28153 | 0.83 | ATM (1.00) | ATMHCAR2HPGDTSHRMAPT | |
| SCHEMBL10423863 | 0.83 | ATM (1.00) | ATMHCAR2HPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132375-B1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6531624-B1 | Intermediates of quinolone antibiotics;3-dimethylamino-2-(2,4,5-trifluoro-3-methyl-6 -nitrobenzoyl)acrylates | ASAHI GLASS COMPANY LTD. (JP) | 2003-03-11 | — | — | US | disclosed |
| EP-1132375-A1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |