SCHEMBL7083152

SCHEMBL7083152

CCCOC(=O)/C=C/N(C)C

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.59
ATM Q13315 1/20 0.52
APP P05067 2/20 0.42
ALOX5 P09917 1/20 0.41
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171459 1.00 HCAR2 (0.59) HCAR2ATMAPPALOX5MAPT
Hydrochloric Acid SCHEMBL8108663 0.98 HCAR2 (0.57) HCAR2ATMAPPALOX5MAPT
SCHEMBL21126304 0.89 ATM (0.46) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7083235 0.88 ATM (0.70) HCAR2ATMAPPMAPTRAB9A
SCHEMBL7083237 0.88 ATM (0.70) HCAR2ATMAPPMAPTRAB9A
SCHEMBL27411593 0.85 HCAR2 (0.64) HCAR2ATMAPPMAPTRAB9A
SCHEMBL21126695 0.83 ATM (0.52) HCAR2ATMAPPMAPTRAB9A
SCHEMBL8354202 0.83 HCAR2 (0.56) HCAR2ATMMAPTNPSR1KMT2A
SCHEMBL286141 0.83 HCAR2 (0.56) HCAR2ATMMAPTNPSR1KMT2A
SCHEMBL286112 0.83 HCAR2 (0.56) HCAR2ATMMAPTNPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106918999-B Colored photosensitive resin composition, color filter and image display device 东友精细化工有限公司 2021-11-23 CN disclosed
EP-1132375-B1 AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME ASAHI GLASS CO LTD (JP) 2003-07-16 EP disclosed
US-6531624-B1 Intermediates of quinolone antibiotics;3-dimethylamino-2-(2,4,5-trifluoro-3-methyl-6 -nitrobenzoyl)acrylates ASAHI GLASS COMPANY LTD. (JP) 2003-03-11 US disclosed
EP-1132375-A1 AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME ASAHI GLASS COMPANY LTD. (JP) 2001-09-12 EP disclosed