⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592264 | 0.82 | — | — | |
| SCHEMBL6510727 | 0.70 | — | — | |
| SCHEMBL8696448 | 0.67 | DPP4 (0.34) | — | |
| SCHEMBL5454983 | 0.67 | TP53 (0.31) | — | |
| SCHEMBL1287867 | 0.66 | LMNA (0.30) | — | |
| SCHEMBL8727451 | 0.62 | — | — | |
| SCHEMBL7963281 | 0.62 | — | — | |
| Tromethamine SCHEMBL1508805 | 0.62 | LMNA (0.67) | — | |
| Tromethamine SCHEMBL5988271 | 0.62 | LMNA (0.67) | — | |
| Tromethamine SCHEMBL4939766 | 0.62 | LMNA (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126920-A | High-yield aureomycin engineering strain based on malonyl-CoA regeneration pathway | 中国科学院西北生态环境资源研究院 | 2024-06-04 | — | — | CN | claimed |
| EP-0592242-B1 | Fibrin sealant compositions and method for utilizing same | SQUIBB & SONS INC (US) | 2003-07-09 | — | — | EP | claimed |
| US-5750657-A | Methods and compositions using fibrin monomer to make a fibrin sealant | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-12 | — | — | US | claimed |
| EP-0592242-A1 | Fibrin sealant compositions and method for utilizing same | E.R. SQUIBB & SONS, INC. (US) | 1994-04-13 | — | — | EP | claimed |
| CN-118126920-A | High-yield aureomycin engineering strain based on malonyl-CoA regeneration pathway | 中国科学院西北生态环境资源研究院 | 2024-06-04 | — | — | CN | disclosed |
| CN-115141797-B | Frozen semen thawing agent for pigs and preparation method thereof | 华中农业大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-116926144-A | Method for preparing teldamycin by using Streptomyces gossypii TRM44567 strain | 塔里木大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116333950-A | Genetically engineered bacterium for high yield of oleanolic acid, construction method and application thereof | 武汉大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116333951-A | Genetically engineered bacterium for high yield of azalomycin F, construction method and application thereof | 武汉大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116298276-A | Frozen concentrated buffer solution and application thereof in storage of SARS-CoV-2 antigen detection reagent | 桂林电子科技大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-112166318-B | Electrical circuit for electrochemical measurement and measurement device | 株式会社普欧威盖特 | 2023-06-23 | — | — | CN | disclosed |
| CN-116042405-A | Scenedesmus strain and application thereof in domestic sewage treatment and grease production | 山东省农业科学院 | 2023-05-02 | — | — | CN | disclosed |
| US-5770194-A | APPLYING ENZYMATICALLY CLEAVED FIBRIN FOR CLOT FORMATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5763411-A | SOLID SUPPORT COATED WITH FIBRIN MONOMER READILY CAPABLE OF BEING CONVERTED TO FIBRIN POLYMER SEALANT OR HEMOSTAT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5763410-A | Kit for preparing a fibrin sealant | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5750657-A | Methods and compositions using fibrin monomer to make a fibrin sealant | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5739288-A | BLOOD COAGULANTS COMPRISING ANTIBIOTICS, ANTICARCINOGENIC AGENT AND HISTAMINE H2-ANTAGONIST; PREVENTING INFECTIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0654078-A1 | A THROMBIN BLOOD FRACTION FOR USE IN A MEDICAL PROCEDURE | E.R. SQUIBB & SONS, INC. (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0592242-A1 | Fibrin sealant compositions and method for utilizing same | E.R. SQUIBB & SONS, INC. (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1994000566-A1 | A THROMBIN BLOOD FRACTION FOR USE IN A MEDICAL PROCEDURE | E.R. SQUIBB & SONS INC. (US) | 1994-01-06 | — | — | WO | disclosed |