SCHEMBL7083441

SCHEMBL7083441

CCCCN(Cc1cccc(C(=N)NC(=O)OC(C)N(CC)CC)c1)C(=O)Oc1ccc(-c2ccccc2S(N)(=O)=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 12/20 0.43
F2 P00734 9/20 0.41
PRSS1 P07477 9/20 0.41
PRSS2 P07478 8/20 0.41
PRSS3 P35030 8/20 0.41
PLG P00747 2/20 0.41
PLAT P00750 2/20 0.41
F7 P08709 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7087150 0.98 F10 (0.43) F10F2PRSS1PRSS2PRSS3
SCHEMBL7090573 0.96 F10 (0.44) F10F2PRSS1PRSS2PRSS3
SCHEMBL7084341 0.94 F10 (0.44) F10F2PRSS1PRSS2PRSS3
SCHEMBL7089953 0.93 F10 (0.47) F10F2PRSS1PRSS2PRSS3
SCHEMBL7086921 0.92 F10 (0.43) F10F2PRSS1PRSS2PRSS3
SCHEMBL7087643 0.91 F10 (0.48) F10F2PRSS1PRSS2PRSS3
SCHEMBL7088626 0.90 F10 (0.50) F10F2PRSS1PRSS2PRSS3
SCHEMBL7073268 0.90 F2 (0.45) F10F2PRSS1PRSS2PRSS3
SCHEMBL7087031 0.89 F10 (0.42) F10F2PRSS1PRSS2PRSS3
SCHEMBL7087154 0.89 F10 (0.42) F10F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa MERCK PATENT GMBH (DE) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa F11, F12, F13A1 F10 5/4885F2 4/4885PRSS1 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.