Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 14/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135092 | 0.92 | F10 (0.45) | SCN9AF10PRSS1 | |
| SCHEMBL7089660 | 0.92 | F10 (0.40) | SCN9AF10PRSS1 | |
| SCHEMBL7089702 | 0.92 | F10 (0.41) | SCN9AF10PRSS1 | |
| SCHEMBL7086977 | 0.91 | F10 (0.42) | SCN9AF10PRSS1 | |
| SCHEMBL7087186 | 0.90 | F10 (0.40) | SCN9AF10PRSS1 | |
| SCHEMBL7087123 | 0.90 | F10 (0.38) | F10PRSS1 | |
| SCHEMBL7074225 | 0.89 | SCN9A (0.41) | SCN9AF10PRSS1SCN10A | |
| SCHEMBL7087207 | 0.89 | F10 (0.41) | SCN9AF10PRSS1 | |
| SCHEMBL7093611 | 0.89 | F10 (0.45) | F10PRSS1 | |
| SCHEMBL7090609 | 0.89 | F10 (0.41) | SCN9AF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | MERCK PATENT GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | F11, F12, F13A1 | SCN9A 1400/4885F10 5/4885PRSS1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.