Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083783 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL7494954 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL7494965 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL7490138 | 0.87 | LMNA (0.42) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL7490130 | 0.87 | LMNA (0.42) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL5787723 | 0.87 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL5787718 | 0.87 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL5786070 | 0.86 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL5786068 | 0.86 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL6333639 | 0.86 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071665-B1 | SUBSTITUTED INDOLINONES HAVING AN INHIBITING EFFECT ON KINASES AND CYCLINE/CDK COMPLEXES | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-01 | — | — | EP | disclosed |