Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.71 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.71 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.71 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.58 |
| ▸ | RRM1 | P23921 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 4/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965247 | 1.00 | GNAI3 (0.71) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL24179776 | 0.98 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL10033848 | 0.98 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12085475 | 0.98 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965329 | 0.97 | GNAI3 (0.71) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965246 | 0.97 | GNAI3 (0.71) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965169 | 0.95 | GNAI3 (0.64) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5497912 | 0.95 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965168 | 0.93 | GNAI3 (0.67) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965319 | 0.93 | GNAI3 (0.67) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040096-B1 | NEUROPROTECTIVE AGENTS | UNIV SOUTHAMPTON (GB) | 2003-07-09 | — | — | EP | disclosed |
| EP-1040096-A1 | NEUROPROTECTIVE AGENTS | THE UNIVERSITY OF SOUTHAMPTON (GB) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031049-A1 | NEUROPROTECTIVE AGENTS | UNIVERSITY OF SOUTHAMPTON (GB) | 1999-06-24 | — | — | WO | disclosed |