SCHEMBL708379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707552	0.86	POLB (0.50)	POLBLMNAKDM4EALDH1A1RECQL
	SCHEMBL707714	0.83	LPAR1 (0.51)	POLBLMNAKDM4EPPARGPSEN1
	SCHEMBL709317	0.82	MCL1 (0.47)	POLBLMNAKDM4EPPARGALDH1A1
	SCHEMBL704971	0.81	PPARG (0.48)	POLBLMNAKDM4EPPARGALDH1A1
	SCHEMBL707130	0.80	PPARG (0.54)	POLBLMNAKDM4EPPARG
	SCHEMBL708371	0.80	POLB (0.54)	POLBLMNAKDM4EALDH1A1RECQL
	SCHEMBL709389	0.73	PSEN1 (0.55)	POLBLMNAKDM4EPPARGPSEN1
	SCHEMBL705825	0.73	SRD5A2 (0.57)	POLBKDM4EALDH1A1
	SCHEMBL6047767	0.72	POLB (0.57)	POLBLMNAACSS2KDM4EALDH1A1
	SCHEMBL4696808	0.72	POLB (0.57)	POLBLMNAACSS2KDM4EPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.