SCHEMBL709389

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707714	0.90	LPAR1 (0.51)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL708944	0.75	LPAR1 (0.52)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL707130	0.74	PPARG (0.54)	POLBLMNAPPARGLPAR1KDM4E
	SCHEMBL708379	0.73	POLB (0.51)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL707552	0.71	POLB (0.50)	POLBLMNANPSR1ALDH1A1RECQL
	SCHEMBL4696808	0.70	POLB (0.57)	POLBLMNANPSR1PPARGALDH1A1
	SCHEMBL6047758	0.70	POLB (0.57)	POLBLMNAPPARGALDH1A1RECQL
	SCHEMBL6047767	0.70	POLB (0.57)	POLBLMNANPSR1ALDH1A1RECQL
	SCHEMBL13851461	0.70	HTT (0.67)	POLBLPAR1LPAR3ALDH1A1SMN1; SMN2
	SCHEMBL6047817	0.70	POLB (0.52)	POLBLMNANPSR1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.