Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.44 |
| ▸ | FNTB | P49356 | 13/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084240 | 1.00 | FNTA (0.44) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL6927124 | 0.84 | FNTA (0.47) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL7675140 | 0.84 | HTR2C (0.42) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL7547465 | 0.81 | FNTA (0.41) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL7512901 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL6983262 | 0.79 | HTR2C (0.45) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL7503289 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL7509342 | 0.78 | FNTA (0.42) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL7508235 | 0.78 | FNTA (0.43) | FNTAFNTBPGGT1BHTR2CMAPK14 | |
| SCHEMBL6974495 | 0.78 | FNTA (0.49) | FNTAFNTBPGGT1BHTR2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |