Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.49 |
| ▸ | FNTB | P49356 | 14/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648912 | 1.00 | FNTA (0.49) | FNTAFNTBKDM4ECYP3A4PGGT1B | |
| SCHEMBL7648941 | 0.91 | FNTA (0.59) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL6979050 | 0.91 | FNTA (0.59) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL6603204 | 0.82 | FNTA (0.51) | FNTAFNTBKDM4ECYP3A4PGGT1B | |
| SCHEMBL27482595 | 0.82 | FNTA (0.47) | FNTAFNTBKDM4ECYP3A4PGGT1B | |
| SCHEMBL6972971 | 0.82 | FNTA (0.51) | FNTAFNTBKDM4ECYP3A4PGGT1B | |
| SCHEMBL6598325 | 0.78 | FNTA (0.51) | FNTAFNTBKDM4ECYP3A4PGGT1B | |
| SCHEMBL7084240 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL7084119 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1BHTR2CADRA2A | |
| SCHEMBL4955195 | 0.76 | FNTA (0.60) | FNTAFNTBKDM4ECYP3A4PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |