Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.53 |
| ▸ | SCN1A | P35498 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530814 | 0.89 | SLC6A2 (0.46) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL31374423 | 0.84 | CHRM2 (0.69) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL7615187 | 0.78 | CNR2 (0.46) | HRH1HTR2ATSHRHIF1AALDH1A1 | |
| SCHEMBL6681106 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL6679213 | 0.77 | CYP2D6 (0.48) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL9812324 | 0.76 | SLC6A2 (0.63) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL5655181 | 0.76 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2LMNA | |
| SCHEMBL29088831 | 0.76 | SLC6A3 (0.78) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL5655372 | 0.76 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2LMNA | |
| SCHEMBL5655180 | 0.76 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |