Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.40 |
| ▸ | FEN1 | P39748 | 5/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081191 | 0.93 | F10 (0.41) | NAMPTKDRF10ALOX5APFEN1 | |
| SCHEMBL7078594 | 0.92 | F10 (0.41) | NAMPTKDRF10ALOX5APFEN1 | |
| SCHEMBL7084605 | 0.92 | ALOX5AP (0.41) | NAMPTKDRF10ALOX5APFEN1 | |
| SCHEMBL7081398 | 0.91 | NAMPT (0.41) | NAMPTKDRF10ALOX5APFEN1 | |
| SCHEMBL7080721 | 0.90 | KDR (0.44) | NAMPTKDRF10MEN1ALDH1A1 | |
| SCHEMBL7091931 | 0.87 | KDR (0.39) | NAMPTKDRF10ALOX5APFEN1 | |
| SCHEMBL7078082 | 0.86 | GPR119 (0.49) | F10FPR2FPR1ALDH1A1 | |
| SCHEMBL7082152 | 0.83 | F10 (0.44) | NAMPTKDRF10MEN1ALDH1A1 | |
| Acetic Acid SCHEMBL7080660 | 0.82 | F10 (0.48) | F10 | |
| SCHEMBL7078610 | 0.82 | F10 (0.43) | NAMPTKDRF10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | NAMPT 4164/4885KDR 222/4885F10 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.