Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949392 | 0.93 | NPC1 (0.57) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL14599482 | 0.90 | HSD17B10 (0.60) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29575361 | 0.88 | NPC1 (0.61) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL31722789 | 0.88 | NPC1 (0.61) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL2743115 | 0.88 | NPC1 (0.61) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL6629403 | 0.84 | NPC1 (0.61) | HSD17B10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3925183 | 0.82 | PLG (0.62) | HSD17B10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11687709 | 0.81 | TRPV1 (0.60) | NPC1RAB9AKMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL3922499 | 0.81 | PLG (0.61) | HSD17B10NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5060087 | 0.81 | HSD17B10 (1.00) | HSD17B10NPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937753-B1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6239263-B1 | PREPARED FROM A COUPLER CONSISTING OF 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID OR AN ESTER THEREOF OR AN AMIDE DERIVATIVE OF THE SAME AND A DIAZONIUM COMPOUND | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0984042-A1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-6020470-A | Water-soluble azo compounds and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0937753-A1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1999-08-25 | — | — | EP | disclosed |