Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993937 | 0.92 | — | — | |
| SCHEMBL78340 | 0.92 | — | — | |
| SCHEMBL29742199 | 0.90 | KDM4E (0.61) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazine SCHEMBL15798805 | 0.90 | KDM4E (0.61) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyridazine SCHEMBL8009086 | 0.82 | KDM4E (0.53) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL28434671 | 0.81 | KDM4E (0.52) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL27859643 | 0.75 | KDM4E (0.46) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL3186159 | 0.73 | KDM4E (0.70) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL7618500 | 0.73 | KDM4E (0.70) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL27923673 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008046-A1 | USE OF N-NEOHEXYL-A-ASPARTYL-L-PHENYLALANINE METHYL ESTER AS A FLAVOR MODIFIER | NUTRASWEET COMPANY, THE | 2003-01-09 | — | — | US | disclosed |