Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.54 |
| ▸ | STAMBP | O95630 | 1/20 | 0.54 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30547697 | 1.00 | PSMD14 (0.54) | PSMD14STAMBPCOPS5HPGDSABCG2 | |
| SCHEMBL29940529 | 0.85 | PSMD14 (0.53) | PSMD14STAMBPCOPS5ABCG2VNN1 | |
| SCHEMBL2675814 | 0.85 | PSMD14 (0.53) | PSMD14STAMBPCOPS5ABCG2VNN1 | |
| SCHEMBL29688144 | 0.81 | PSMD14 (0.66) | PSMD14STAMBPCOPS5HPGDSPARP1 | |
| SCHEMBL19346770 | 0.81 | PSMD14 (0.66) | PSMD14STAMBPCOPS5HPGDSPARP1 | |
| SCHEMBL29643179 | 0.80 | PSMD14 (0.44) | PSMD14STAMBPCOPS5HPGDSNNMT | |
| Butane SCHEMBL7227124 | 0.79 | PSMD14 (0.47) | PSMD14ABCG2VNN1 | |
| SCHEMBL7220371 | 0.77 | MAOB (0.48) | PSMD14SMN1; SMN2 | |
| SCHEMBL21358860 | 0.74 | PSMD14 (0.61) | PSMD14STAMBPCOPS5HPGDSSMN1; SMN2 | |
| SCHEMBL12483271 | 0.74 | ABCG2 (0.40) | ABCG2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4422404-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2024-09-04 | — | — | EP | claimed |
| WO-2023072785-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-04 | — | — | WO | claimed |
| CN-117177963-A | Microbiocidal quinoline/quinoxaline isoquinoline derivatives | 先正达农作物保护股份公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-115605474-A | Microbicidal quinoline dihydro- (thiazine) oxazine derivatives | 先正达农作物保护股份公司（CH） | 2023-01-13 | — | — | CN | disclosed |
| WO-2017153380-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | WO | disclosed |
| EP-1189903-B1 | NOVEL BENZO[F]NAPHTHYRIDINE, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-28 | — | — | EP | disclosed |
| US-6566362-B2 | Use as topical antibiotics | AVENTIS PHARMA S.A. (FR) | 2003-05-20 | — | — | US | disclosed |
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. (FR) | 2002-09-26 | — | — | US | disclosed |
| EP-1189903-A1 | NOVEL BENZO F]NAPHTHYRIDINE, PREPARATION AND COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001002396-A1 | NOVEL BENZO[F]NAPHTHYRIDINE, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | KCNQ2, KCNQ1, KCNQ4 | PSMD14 1607/4885STAMBP 2415/4885COPS5 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.