Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | USP8 | P40818 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | APOB | P04114 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794575 | 0.90 | MTTP (0.49) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7085703 | 0.89 | AOC3 (0.50) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7162887 | 0.81 | MAPT (0.48) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7079416 | 0.78 | MAPT (0.44) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL6787479 | 0.78 | AOC3 (0.52) | MAPTLMNAHTTAPOBMTTP | |
| SCHEMBL6798726 | 0.77 | NPC1 (0.57) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7138922 | 0.76 | LMNA (0.61) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL6793187 | 0.76 | PTGS1 (0.49) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7083682 | 0.76 | CA12 (0.45) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL7087379 | 0.75 | RXFP1 (0.57) | LMNAPOLBKMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |