Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085735 | 0.77 | CACNA1B (0.40) | CACNA1BNR1I2TYK2CYP3A4CES2 | |
| SCHEMBL8673741 | 0.74 | CACNA1B (0.40) | CACNA1BNR1I2TYK2CYP3A4CES2 | |
| SCHEMBL8673739 | 0.74 | CACNA1B (0.40) | CACNA1BNR1I2TYK2CYP3A4CES2 | |
| SCHEMBL8193270 | 0.74 | ALDH1A1 (0.41) | CYP3A4KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6595780 | 0.74 | MEN1 (0.45) | CACNA1BNR1I2ALDH1A1LMNA | |
| SCHEMBL26411219 | 0.73 | CACNA1B (0.43) | CACNA1BNR1I2TYK2CYP3A4CES2 | |
| SCHEMBL1823768 | 0.73 | CACNA1B (0.46) | CACNA1BNR1I2TYK2CYP3A4KDM4E | |
| SCHEMBL8848783 | 0.72 | KDM4E (0.49) | CACNA1BNR1I2CES2KDM4EALDH1A1 | |
| SCHEMBL8650524 | 0.71 | CACNA1B (0.43) | CACNA1BNR1I2TYK2CYP3A4CES2 | |
| SCHEMBL8650523 | 0.71 | CACNA1B (0.43) | CACNA1BNR1I2TYK2CYP3A4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066270-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-30 | — | — | EP | disclosed |
| US-6255251-B1 | CONTROLLING WEEDS | SYNGENTA CROP PROTECTION, INC. | 2001-07-03 | — | — | US | disclosed |
| EP-1066270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051583-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1999-10-14 | — | — | WO | disclosed |