Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086109 | 1.00 | HCAR2 (0.65) | HCAR2KDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL7089093 | 1.00 | HCAR2 (0.65) | HCAR2KDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL9860565 | 0.94 | HCAR2 (0.56) | HCAR2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL9860571 | 0.94 | HCAR2 (0.56) | HCAR2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5176157 | 0.84 | HCAR2 (0.50) | HCAR2MAPTALDH1A1LMNATSHR | |
| SCHEMBL5176162 | 0.84 | HCAR2 (0.50) | HCAR2MAPTALDH1A1LMNATSHR | |
| SCHEMBL28803484 | 0.81 | HCAR2 (0.69) | HCAR2KDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL27534212 | 0.81 | HCAR2 (0.69) | HCAR2KDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL27545605 | 0.80 | HCAR2 (0.50) | HCAR2KDM4EMAPTALDH1A1HDAC3 | |
| SCHEMBL7083023 | 0.80 | HCAR2 (0.50) | HCAR2KDM4EMAPTALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331494-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS | NOF CORPORATION (JP) | 2003-07-30 | — | — | EP | disclosed |