Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545605 | 1.00 | HCAR2 (0.50) | HCAR2ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL7086112 | 0.80 | HCAR2 (0.65) | HCAR2ALDH1A1KDM4EMAPTHDAC3 | |
| SCHEMBL7089093 | 0.80 | HCAR2 (0.65) | HCAR2ALDH1A1KDM4EMAPTHDAC3 | |
| SCHEMBL7086109 | 0.80 | HCAR2 (0.65) | HCAR2ALDH1A1KDM4EMAPTHDAC3 | |
| SCHEMBL2345812 | 0.80 | ACP3 (0.43) | ALDH1A1KDM4EMAPTACP3IDO1 | |
| SCHEMBL4607561 | 0.77 | ACP3 (0.41) | ALDH1A1KDM4EMAPTACP3IDO1 | |
| SCHEMBL10876491 | 0.76 | CASP1 (0.40) | ALDH1A1KDM4EMAPTACP3IDO1 | |
| SCHEMBL722955 | 0.75 | IDO1 (0.41) | KDM4EMAPTACP3IDO1TDO2 | |
| SCHEMBL9860565 | 0.74 | HCAR2 (0.56) | HCAR2ALDH1A1KDM4EMAPT | |
| SCHEMBL9860571 | 0.74 | HCAR2 (0.56) | HCAR2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331494-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS | NOF CORPORATION (JP) | 2003-07-30 | — | — | EP | disclosed |