Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088989 | 1.00 | HCAR2 (0.40) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL7086300 | 0.92 | HCAR2 (0.53) | HCAR2ATMKEAP1NFE2L2 | |
| SCHEMBL7086292 | 0.92 | HCAR2 (0.53) | HCAR2ATMKEAP1NFE2L2 | |
| SCHEMBL7088991 | 0.92 | HCAR2 (0.53) | HCAR2ATMKEAP1NFE2L2 | |
| SCHEMBL1070261 | 0.83 | TSHR (0.39) | — | |
| SCHEMBL7644476 | 0.83 | HCAR2 (0.44) | HCAR2ATMKEAP1NFE2L2NPSR1 | |
| SCHEMBL7644479 | 0.77 | HCAR2 (0.56) | HCAR2ATM | |
| SCHEMBL7644489 | 0.77 | HCAR2 (0.56) | HCAR2ATM | |
| SCHEMBL27417917 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL11128475 | 0.76 | GAA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331494-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS | NOF CORPORATION (JP) | 2003-07-30 | — | — | EP | disclosed |