Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086394 | 1.00 | KDM4E (0.36) | KDM4EDRD2HTR2AHTR7HTR6 | |
| SCHEMBL6961068 | 0.88 | KDM4E (0.39) | KDM4E | |
| SCHEMBL6961065 | 0.88 | KDM4E (0.39) | KDM4E | |
| SCHEMBL6970030 | 0.86 | KDM4E (0.37) | KDM4E | |
| SCHEMBL6970027 | 0.86 | KDM4E (0.37) | KDM4E | |
| SCHEMBL6966170 | 0.85 | KDM4E (0.36) | KDM4E | |
| SCHEMBL6966166 | 0.85 | KDM4E (0.36) | KDM4E | |
| SCHEMBL7081745 | 0.84 | HSP90B1 (0.33) | — | |
| SCHEMBL7081746 | 0.84 | HSP90B1 (0.33) | — | |
| SCHEMBL6162368 | 0.84 | DRD2 (0.32) | DRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |