Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.85 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086784 | 0.94 | OXTR (0.74) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL5478502 | 0.92 | OXTR (0.72) | OXTRAVPR1ALMNAKDM4EMEN1 | |
| SCHEMBL5478504 | 0.92 | OXTR (0.72) | OXTRAVPR1ALMNAKDM4EMEN1 | |
| SCHEMBL4936354 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL4936174 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL5743785 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL4943198 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL4942975 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL5743780 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 | |
| SCHEMBL4940385 | 0.92 | OXTR (1.00) | OXTRAVPR1ALMNAPKMMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-A1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072705-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-10-04 | — | — | WO | disclosed |