Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258796 | 0.83 | TSHR (0.62) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL27872705 | 0.81 | TSHR (0.60) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL28284771 | 0.81 | TSHR (0.60) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL17546158 | 0.81 | KAT2B (0.60) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL2371809 | 0.81 | TSHR (0.60) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| Hydrochloric Acid SCHEMBL3009620 | 0.80 | KAT2B (0.61) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL4626839 | 0.80 | TSHR (0.53) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL27264988 | 0.79 | ALDH1A1 (0.58) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1704376 | 0.79 | ALDH1A1 (0.71) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 | |
| SCHEMBL10252732 | 0.79 | TSHR (0.56) | TSHRCYP3A4KAT2BALDH1A1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079829-B1 | USE OF BENZOFUROXAN DERIVATIVES IN TREATING ANGINA PECTORIS | TORRENT PHARMACEUTICALS LTD (IN) | 2003-07-23 | — | — | EP | disclosed |
| CN-1302205-A | Use of benzofuroxan derivatives for treating angina pectoris | TORANTO MEDICINE CO LTD (IN) | 2001-07-04 | — | — | CN | disclosed |
| US-6232331-B1 | TOLERANCE RESISTANT NITRIC OXIDE DONORS IN TREATMENT OF ANGINA PECTORIS | TORRENT PHARMACEUTICAL LTD. (IN) | 2001-05-15 | — | — | US | disclosed |